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Assess sepsis risk using SIRS criteria and physiological parameters for clinical decision support. Our medical calculator supports healthcare professionals with systematic sepsis screening and risk stratification tools.
Last updated: February 2, 2026
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Normal range: 36.0-37.5°C
Normal: 60-90 bpm
Normal: 12-20/min
Normal: 4.0-12.0 K/μL
Normal: <10%
Risk Level:
SIRS Positive
Score:
2/4 criteria
Probability:
15%
Assessment:
SIRS Assessment
Clinical Recommendation:
Patient meets SIRS criteria. Consider sepsis workup including blood cultures, lactate level, and source identification.
Patient has 2/4 SIRS criteria positive, indicating systemic inflammatory response.
Calculation Details:
Medical Disclaimer:
This calculator is for educational purposes only and should not replace clinical judgment. Always consider the complete clinical picture, patient history, and consult with healthcare professionals for diagnosis and treatment decisions. SIRS criteria have limitations and newer sepsis definitions (Sepsis-3) may be more appropriate in some settings.
For patient with T=38.5°C, HR=95 bpm, RR=18/min, WBC=8.5:
SIRS Positive (2/4 criteria)
Moderate sepsis risk - consider workup if infection suspected
Our Kaiser sepsis calculator applies evidence-based SIRS criteria to systematically assess sepsis risk in clinical settings. The calculator uses physiological parametersto provide standardized screening and clinical decision support for healthcare professionals.
>38.3°C (101°F) or <36°C (96.8°F)>90 beats per minute (tachycardia)>20 breaths per minute (tachypnea)<4,000 or >12,000 cells/μL, or >10% bandsSIRS is diagnosed when 2 or more criteria are present. In the context of suspected infection, SIRS indicates sepsis. These criteria help standardize the recognition of systemic inflammatory response and guide early intervention.
Shows how the body responds to systemic inflammation and infection
The SIRS-based approach to sepsis recognition has been fundamental in emergency medicine and critical care. While newer definitions emphasize organ dysfunction (Sepsis-3), SIRS criteria remain valuable for early screening and clinical decision-making. The systematic evaluation of physiological parameters helps identify patients who may benefit from further evaluation and early intervention.
This calculator is designed for educational purposes and clinical decision support for qualified healthcare professionals. It should not replace comprehensive clinical assessment, professional medical judgment, or established institutional protocols. Always consider the complete clinical picture, patient history, and current evidence-based guidelines when making diagnostic and treatment decisions.
Contact for Healthcare IntegrationResult: SIRS Positive (4/4 criteria) - Very High Risk
Clinical Action: This patient meets all SIRS criteria with suspected infection, indicating sepsis. Immediate interventions should include: blood cultures before antibiotics, serum lactate measurement, fluid resuscitation, empiric broad-spectrum antibiotics, and consideration for ICU admission. The high SIRS score (4/4) suggests significant physiological derangement requiring urgent attention and close monitoring.
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