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Direct answer — Payne corrected calcium formula
Corrected calcium calculator (Payne-style): Corrected Ca (mg/dL) = Total Ca + 0.8 × (4.0 − albumin g/dL). SI units: Total Ca + 0.02 × (40 − albumin g/L). Worked labs: Ca 8.8 mg/dL + albumin 2.5 g/dL → 10 mg/dL (normal corrected despite low total). Teaching normal: 8.5–10.5 mg/dL (2.12–2.62 mmol/L). Prefer ionized calcium in ICU / ESRD. Education only — Payne et al. Br Med J. 1973;4:643-646.
Payne formula, mg/dL vs mmol/L units, and worked labs first — then the interactive calculator. Last updated: August 9, 2026.
Bedside formulas used by this calculator. Classic albumin-adjustment paper: Payne et al. Br Med J. 1973;4:643-646.
| Units | Formula | Worked example |
|---|---|---|
| mg/dL (US / conventional) | Corrected Ca = Total Ca + 0.8 × (4.0 − albumin g/dL) | Ca 8.8, alb 2.5 → 8.8 + 1.2 = 10.0 mg/dL |
| mmol/L (SI) | Corrected Ca = Total Ca + 0.02 × (40 − albumin g/L) | Ca 2.20, alb 25 → 2.20 + 0.30 = 2.50 mmol/L |
| Item | mg/dL system | mmol/L system |
|---|---|---|
| Total calcium units | mg/dL | mmol/L |
| Albumin units | g/dL | g/L |
| Reference albumin | 4.0 g/dL | 40 g/L |
| Correction factor | 0.8 mg/dL per g/dL alb | 0.02 mmol/L per g/L alb |
| Teaching normal range | 8.5 – 10.5 mg/dL | 2.12 – 2.62 mmol/L |
Never mix systems (e.g. mg/dL calcium with g/L albumin) in one calculation.
Worked labs example
8.8 + 0.8 × (4 − 2.5) = 10.00 mg/dL → Normal
2.2 + 0.02 × (40 − 25) = 2.50 mmol/L → Normal
Toggle mg/dL or mmol/L to match the Payne formulas above. Result shows arithmetic string and teaching band.
Correction formulas ignore pH, citrate, and many ICU binding shifts. Use ionized calcium for critical decisions.
Normal range: 8.5–10.5 mg/dL
Normal range: 3.5–5.0 g/dL
Corrected Calcium:
9.9 mg/dL
9.5 + 0.8 × (4 − 3.5) = 9.90 mg/dL
Interpretation:
Normal
Normal Range:
8.5 – 10.5 mg/dL
Clinical Analysis:
Corrected calcium is within the teaching normal range. Interpret with symptoms, ionized calcium when available, and clinical context.
Medical Disclaimer:
Teaching cutoffs for interpretation on this page — confirm against your laboratory reference interval.
| Band | mg/dL | mmol/L | Note |
|---|---|---|---|
| Hypocalcemia | < 8.5 mg/dL | < 2.12 mmol/L | Consider Vit D, PTH, Mg²⁺, CKD — confirm with ionized Ca when critical |
| Normal (teaching) | 8.5 – 10.5 mg/dL | 2.12 – 2.62 mmol/L | Lab reference intervals may vary ±0.1–0.2 |
| Hypercalcemia | > 10.5 mg/dL | > 2.62 mmol/L | Consider PTH, malignancy, Vit D toxicity, thiazides |
| Situation | Action |
|---|---|
| Low albumin (malnutrition, cirrhosis, nephrosis) | Correct total Ca — hypoalbuminemia falsely lowers total Ca |
| High albumin (dehydration, rare) | Correct — hyperalbuminemia can raise total Ca |
| Albumin ≈ 4.0 g/dL (40 g/L) | Correction ≈ 0 — total Ca already usable |
| Critical illness, shock, massive transfusion | Prefer ionized calcium — binding shifts with pH/lactate |
| ESRD / dialysis | Prefer ionized Ca — Payne formula less reliable |
| Acute alkalosis or acidosis | Prefer ionized Ca — pH alters binding; formula ignores pH |
Default — Ca 9.5, alb 3.5
9.9 mg/dL
Normal
Worked labs — Ca 8.8, alb 2.5
10 mg/dL
Low total → normal corrected
Same case — SI units
2.5 mmol/L
Ca 2.20, alb 25 g/L
Masked high — Ca 10.2, alb 2.0
11.8 mg/dL
Hypercalcemia (High)
Same total calcium (8.8 mg/dL) across falling albumin — correction rises as albumin falls.
| Total Ca | Albumin | Corrected | Band | Arithmetic |
|---|---|---|---|---|
| 8.8 | 2 | 10.4 mg/dL | Normal | 8.8 + 0.8 × (4 − 2) = 10.40 mg/dL |
| 8.8 | 2.5 | 10 mg/dL | Normal | 8.8 + 0.8 × (4 − 2.5) = 10.00 mg/dL |
| 8.8 | 3 | 9.6 mg/dL | Normal | 8.8 + 0.8 × (4 − 3) = 9.60 mg/dL |
| 8.8 | 4 | 8.8 mg/dL | Normal | 8.8 + 0.8 × (4 − 4) = 8.80 mg/dL |
| 9.5 | 3.5 | 9.9 mg/dL | Normal | 9.5 + 0.8 × (4 − 3.5) = 9.90 mg/dL |
1. Albumin deficit = 4.0 − 2.5 = 1.5 g/dL
2. Correction = 0.8 × 1.5 = 1.2 mg/dL
3. Corrected Ca = 8.8 + 1.2 = 10 mg/dL
4. Interpretation: Normal (8.5 – 10.5 mg/dL)
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